I love Trader Joes and would love to see one in Blacksburg, but what would this do to Eats and Annie Kay's? I do think it's definitely a un-filled niche downtown though — Annie Kay's made a terrible decision to move all the way down South Main Street.
I've heard of a number of people with a serious interest in buying the old bank at Roanoke and Main and converting into a music venue: proposals include everything from a dance club to a dueling piano bar. Apparently, the issue however, lies with the owner and the building itself. It had not been up-kept and in order to evict the last tenant the owner let it become condemned - supposedly for a structural issue. I'm unsure what would need to be done to make this building safe again, but one thing for sure is there is much interest in repurposing it.